Common brain disorders are associated with heritable patterns of apparent aging of the brain

Author(s)

Publication date

2019-07-22

Series/Report no

Nature Neuroscience;Volume 22, Issue 10

Publisher

Nature Research (part of Springer Nature)

Document type

Abstract

Common risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life. Using structural MRI data from 45,615 individuals aged 3–96 years, we demonstrate distinct patterns of apparent brain aging in several brain disorders and reveal genetic pleiotropy between apparent brain aging in healthy individuals and common brain disorders.

Keywords

Version

acceptedVersion

Permanent URL (for citation purposes)

  • https://hdl.handle.net/10642/7874